AF-related stroke risk reduction

Anticoagulants are a medication taken to reduce the risk of stroke caused by AF. They work by slowing down the clotting process of the blood.

Oral anticoagulants:

Warfarin is the oldest anticoagulant and has been tried and tested for decades. Warfarin works with vitamin K in the body to inhibit clotting, and because levels of vitamin K vary from week to week, regular blood tests are needed to check what are known as INR (International normalised ratio) levels which affect the dose of warfarin needed.

Since 2012, three so-called novel anticoagulants (NOACs) have been approved for use in the UK, namely dabigatran,rivaroxaban and apixaban. These work in a different way from warfarin and the daily dose is relatively constant compared with warfarin. A fourth NOAC, edoxaban, may be introduced in the UK in the next few years subject to approval from NICE.

Information on oral anticoagulation for clinicians and commissioners is available here

Other options

Heparin is an injectable anticoagulant which starts working very quickly and this is used on some patients during an operation. Heparin is not a viable alternative for home use because of its very short half-life.

Left atrial appendage occlusion (LAAO)

For those who are unable to tolerate anticoagulants for medical reasons, there is a procedure known as LAAO or Transcatheter Closure of the left atrial appendage. This closes totally or partially the small pouch off the heart (the LAA) in which clots can form. LAAO has comparable risk-prevention capability as anticoagulation.


Description: http://www.atrialfibrillation.org.uk/files/image/Images/Alert%20card.JPG

Anticoagulant alert card

If you are taking anticoagulant therapy, download this pocket-sized 'anticoagulant alert card' to keep on you at all times in case of a medical emergency.

Download card or alternatively call AF Association Patient Services on 01789 867502 to obtain one.

Get in touch for more help and information



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